2025 Big 12 Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 10/14/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | BYU | 3 | 133 | 483 | 177 | 616 | 3.48 | 205.3 |
| 2 | Utah | 3 | 270 | 402 | 165 | 672 | 4.07 | 224.0 |
| 3 | Texas Tech | 3 | 124 | 568 | 186 | 692 | 3.72 | 230.7 |
| 4 | Arizona | 2 | 183 | 291 | 131 | 474 | 3.62 | 237.0 |
| 5 | UCF | 3 | 388 | 351 | 189 | 739 | 3.91 | 246.3 |
| 6 | Houston | 3 | 405 | 357 | 206 | 762 | 3.70 | 254.0 |
| 7 | Iowa State | 3 | 374 | 431 | 187 | 805 | 4.30 | 268.3 |
| 8 | Cincinnati | 3 | 276 | 551 | 200 | 827 | 4.14 | 275.7 |
| 9 | West Virginia | 3 | 281 | 620 | 210 | 901 | 4.29 | 300.3 |
| 10 | Kansas | 3 | 351 | 603 | 192 | 954 | 4.97 | 318.0 |
| 11 | Arizona State | 3 | 274 | 705 | 212 | 979 | 4.62 | 326.3 |
| 12 | Kansas State | 2 | 339 | 347 | 154 | 686 | 4.45 | 343.0 |
| 13 | TCU | 3 | 321 | 738 | 189 | 1059 | 5.60 | 353.0 |
| 14 | Baylor | 3 | 565 | 503 | 193 | 1068 | 5.53 | 356.0 |
| 15 | Colorado | 3 | 569 | 637 | 201 | 1206 | 6.00 | 402.0 |
| 16 | Oklahoma State | 3 | 633 | 647 | 196 | 1280 | 6.53 | 426.7 |