2025 Big 12 Conference Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 10/14/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Kansas | 1 | 37 | 179 | 58 | 216 | 3.72 | 216.0 |
| 2 | Houston | 1 | 177 | 51 | 66 | 228 | 3.45 | 228.0 |
| 2 | Texas Tech | 1 | 63 | 165 | 59 | 228 | 3.86 | 228.0 |
| 4 | Utah | 1 | 121 | 108 | 57 | 229 | 4.02 | 229.0 |
| 5 | Arizona | 1 | 67 | 223 | 76 | 290 | 3.82 | 290.0 |
| 6 | Arizona State | 1 | 119 | 184 | 78 | 303 | 3.88 | 303.0 |
| 7 | UCF | 1 | 165 | 157 | 69 | 322 | 4.67 | 322.0 |
| 8 | Kansas State | 1 | 237 | 95 | 82 | 332 | 4.05 | 332.0 |
| 9 | Colorado | 2 | 249 | 494 | 133 | 743 | 5.59 | 371.5 |
| 10 | Cincinnati | 1 | 98 | 274 | 71 | 372 | 5.24 | 372.0 |
| 11 | Iowa State | 1 | 160 | 222 | 73 | 382 | 5.23 | 382.0 |
| 12 | BYU | 1 | 119 | 285 | 77 | 404 | 5.25 | 404.0 |
| 13 | Oklahoma State | 1 | 205 | 219 | 79 | 424 | 5.37 | 424.0 |
| 14 | West Virginia | 1 | 182 | 247 | 79 | 429 | 5.43 | 429.0 |