2025 Conference USA Leaders Sacks Allowed - Games vs. FBS Power 5 Conference Teams Only through 11/01/2025
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Delaware | 1 | 2.0 | 5 | 2.00 |
| 1 | UTEP | 1 | 2.0 | 6 | 2.00 |
| 1 | Louisiana Tech | 1 | 2.0 | 10 | 2.00 |
| 1 | Jacksonville State | 1 | 2.0 | 13 | 2.00 |
| 5 | FIU | 1 | 3.0 | 16 | 3.00 |
| 6 | Kennesaw State | 2 | 4.0 | 15 | 2.00 |
| 7 | Sam Houston State | 1 | 5.0 | 26 | 5.00 |
| 7 | Middle Tennessee State | 1 | 5.0 | 40 | 5.00 |
| 9 | Missouri State | 2 | 10.0 | 59 | 5.00 |