2025 Conference USA Leaders Sacks Allowed - Games vs. FBS Power 5 Conference Teams Only through 11/22/2025
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | UTEP | 1 | 2.0 | 6 | 2.00 |
| 1 | Jacksonville State | 1 | 2.0 | 13 | 2.00 |
| 1 | Kennesaw State | 2 | 4.0 | 15 | 2.00 |
| 1 | Delaware | 2 | 4.0 | 19 | 2.00 |
| 5 | Louisiana Tech | 2 | 5.0 | 25 | 2.50 |
| 6 | FIU | 1 | 3.0 | 16 | 3.00 |
| 6 | New Mexico State | 1 | 3.0 | 40 | 3.00 |
| 6 | Sam Houston State | 2 | 6.0 | 32 | 3.00 |
| 9 | Western Kentucky | 1 | 5.0 | 39 | 5.00 |
| 9 | Middle Tennessee State | 1 | 5.0 | 40 | 5.00 |
| 9 | Missouri State | 2 | 10.0 | 59 | 5.00 |