2025 Conference USA Leaders Opponent First Downs - Games in October Only through 11/22/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Liberty | 2 | 15 | 15 | 2 | 32 | 16.0 |
| 2 | UTEP | 3 | 23 | 29 | 8 | 60 | 20.0 |
| 3 | Kennesaw State | 3 | 24 | 32 | 5 | 61 | 20.3 |
| 4 | Jacksonville State | 3 | 15 | 33 | 7 | 55 | 18.3 |
| 4 | Middle Tennessee State | 3 | 23 | 33 | 7 | 63 | 21.0 |
| 4 | Louisiana Tech | 3 | 25 | 33 | 5 | 63 | 21.0 |
| 7 | Sam Houston State | 4 | 52 | 34 | 8 | 94 | 23.5 |
| 8 | New Mexico State | 3 | 18 | 37 | 4 | 59 | 19.7 |
| 8 | Delaware | 3 | 22 | 37 | 5 | 64 | 21.3 |
| 10 | FIU | 4 | 35 | 38 | 5 | 78 | 19.5 |
| 11 | Missouri State | 3 | 18 | 39 | 8 | 65 | 21.7 |
| 12 | Western Kentucky | 3 | 23 | 41 | 8 | 72 | 24.0 |