2025 Conference USA Leaders Opponent First Downs - Games Lost Only through 11/01/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 2 | 19 | 18 | 5 | 42 | 21.0 |
| 2 | Kennesaw State | 2 | 22 | 23 | 3 | 48 | 24.0 |
| 3 | Louisiana Tech | 3 | 19 | 41 | 10 | 70 | 23.3 |
| 4 | Jacksonville State | 3 | 37 | 30 | 5 | 72 | 24.0 |
| 5 | Missouri State | 3 | 25 | 41 | 10 | 76 | 25.3 |
| 6 | Liberty | 4 | 47 | 32 | 5 | 84 | 21.0 |
| 7 | Delaware | 4 | 38 | 42 | 6 | 86 | 21.5 |
| 8 | FIU | 5 | 48 | 46 | 10 | 104 | 20.8 |
| 9 | UTEP | 6 | 58 | 44 | 13 | 115 | 19.2 |
| 10 | New Mexico State | 5 | 47 | 59 | 11 | 117 | 23.4 |
| 11 | Middle Tennessee State | 7 | 60 | 73 | 14 | 147 | 21.0 |
| 12 | Sam Houston State | 8 | 83 | 95 | 13 | 191 | 23.9 |