2025 Conference USA Leaders Scoring Defense - Games vs. Unranked Teams Only (AP Poll) through 10/08/2025
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 4 | 5 | 3 | 4 | 1 | 0 | 45 | 11.3 |
| 2 | Kennesaw State | 4 | 8 | 2 | 6 | 0 | 0 | 60 | 15.0 |
| 3 | New Mexico State | 5 | 14 | 5 | 13 | 1 | 0 | 114 | 22.8 |
| 4 | Liberty | 6 | 15 | 6 | 14 | 1 | 0 | 124 | 20.7 |
| 4 | Western Kentucky | 6 | 15 | 11 | 14 | 0 | 0 | 137 | 22.8 |
| 6 | UTEP | 6 | 17 | 11 | 15 | 1 | 0 | 152 | 25.3 |
| 6 | Delaware | 5 | 16 | 7 | 15 | 0 | 0 | 132 | 26.4 |
| 8 | Jacksonville State | 5 | 17 | 5 | 17 | 0 | 0 | 134 | 26.8 |
| 9 | FIU | 5 | 19 | 9 | 19 | 0 | 0 | 160 | 32.0 |
| 10 | Middle Tennessee State | 6 | 22 | 8 | 21 | 0 | 0 | 177 | 29.5 |
| 11 | Missouri State | 6 | 22 | 8 | 22 | 0 | 0 | 178 | 29.7 |
| 12 | Sam Houston State | 5 | 25 | 11 | 25 | 0 | 0 | 208 | 41.6 |