2025 Conference USA Leaders Scoring Defense - Games vs. Unranked Teams Only (AP Poll) through 11/22/2025
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jacksonville State | 11 | 38 | 9 | 30 | 1 | 0 | 287 | 26.1 |
| 2 | Kennesaw State | 10 | 25 | 10 | 21 | 1 | 0 | 203 | 20.3 |
| 2 | Missouri State | 9 | 24 | 10 | 23 | 0 | 0 | 197 | 21.9 |
| 4 | New Mexico State | 10 | 32 | 11 | 31 | 1 | 0 | 258 | 25.8 |
| 5 | Liberty | 10 | 29 | 12 | 25 | 2 | 0 | 239 | 23.9 |
| 5 | Middle Tennessee State | 11 | 45 | 12 | 41 | 0 | 0 | 347 | 31.5 |
| 7 | Louisiana Tech | 11 | 26 | 14 | 22 | 3 | 0 | 226 | 20.5 |
| 8 | FIU | 11 | 39 | 15 | 38 | 0 | 0 | 317 | 28.8 |
| 8 | Sam Houston State | 10 | 43 | 15 | 40 | 0 | 0 | 343 | 34.3 |
| 10 | UTEP | 10 | 32 | 17 | 30 | 1 | 1 | 277 | 27.7 |
| 10 | Delaware | 11 | 44 | 17 | 42 | 1 | 0 | 359 | 32.6 |
| 12 | Western Kentucky | 11 | 25 | 24 | 22 | 0 | 0 | 244 | 22.2 |