2025 Conference USA Leaders Scoring Defense - Games vs. FBS non-Power 5 Conference Teams Only through 11/22/2025
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Louisiana Tech | 8 | 20 | 11 | 16 | 3 | 0 | 175 | 21.9 |
| 2 | Kennesaw State | 8 | 22 | 9 | 19 | 1 | 0 | 180 | 22.5 |
| 3 | Missouri State | 8 | 23 | 9 | 22 | 0 | 0 | 187 | 23.4 |
| 4 | Western Kentucky | 9 | 24 | 20 | 21 | 0 | 0 | 225 | 25.0 |
| 5 | UTEP | 9 | 30 | 16 | 28 | 1 | 1 | 260 | 28.9 |
| 6 | Liberty | 10 | 32 | 13 | 28 | 2 | 0 | 263 | 26.3 |
| 6 | New Mexico State | 9 | 32 | 10 | 31 | 1 | 0 | 255 | 28.3 |
| 6 | Delaware | 8 | 32 | 12 | 31 | 0 | 0 | 259 | 32.4 |
| 9 | Jacksonville State | 9 | 35 | 7 | 27 | 1 | 0 | 260 | 28.9 |
| 9 | Middle Tennessee State | 9 | 35 | 10 | 31 | 0 | 0 | 271 | 30.1 |
| 9 | FIU | 9 | 35 | 10 | 34 | 0 | 0 | 274 | 30.4 |
| 12 | Sam Houston State | 9 | 41 | 14 | 38 | 0 | 0 | 326 | 36.2 |