2022 American Athletic Conference Leaders Sacks - Games in October Only through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Cincinnati | 4 | 18.0 | 120 | 4.50 |
| 2 | Temple | 4 | 14.0 | 68 | 3.50 |
| 3 | East Carolina | 5 | 14.0 | 84 | 2.80 |
| 4 | Houston | 3 | 8.0 | 41 | 2.67 |
| 5 | SMU | 4 | 9.0 | 56 | 2.25 |
| 6 | Navy | 5 | 9.0 | 45 | 1.80 |
| 7 | South Florida | 4 | 7.0 | 36 | 1.75 |
| 8 | UCF | 4 | 6.0 | 54 | 1.50 |
| 9 | Tulane | 3 | 4.0 | 21 | 1.33 |
| 10 | Memphis | 4 | 5.0 | 26 | 1.25 |
| 11 | Tulsa | 4 | 4.0 | 31 | 1.00 |