2022 American Athletic Conference Leaders Total Defense - Games vs. FBS (I-A) Teams Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 12 | 1850 | 2258 | 869 | 4108 | 4.73 | 342.3 |
| 2 | Tulane | 13 | 2072 | 2864 | 963 | 4936 | 5.13 | 379.7 |
| 3 | Memphis | 12 | 1487 | 3113 | 849 | 4600 | 5.42 | 383.3 |
| 4 | UCF | 13 | 2177 | 3056 | 886 | 5233 | 5.91 | 402.5 |
| 4 | Temple | 11 | 2284 | 2300 | 776 | 4584 | 5.91 | 416.7 |
| 4 | Houston | 13 | 1859 | 3622 | 928 | 5481 | 5.91 | 421.6 |
| 7 | Tulsa | 11 | 2287 | 2389 | 779 | 4676 | 6.00 | 425.1 |
| 8 | Navy | 11 | 1054 | 2813 | 642 | 3867 | 6.02 | 351.5 |
| 9 | East Carolina | 12 | 1359 | 3506 | 791 | 4865 | 6.15 | 405.4 |
| 10 | SMU | 12 | 2543 | 2813 | 858 | 5356 | 6.24 | 446.3 |
| 11 | South Florida | 11 | 2649 | 3134 | 758 | 5783 | 7.63 | 525.7 |