2022 American Athletic Conference Leaders Total Defense - Games on the Road/Neutral Site Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 7 | 987 | 1313 | 493 | 2300 | 4.67 | 328.6 |
| 2 | Navy | 7 | 738 | 1585 | 392 | 2323 | 5.93 | 331.9 |
| 3 | Tulane | 6 | 957 | 1327 | 417 | 2284 | 5.48 | 380.7 |
| 4 | Memphis | 6 | 906 | 1457 | 432 | 2363 | 5.47 | 393.8 |
| 5 | SMU | 7 | 1467 | 1364 | 466 | 2831 | 6.08 | 404.4 |
| 6 | East Carolina | 6 | 726 | 1730 | 396 | 2456 | 6.20 | 409.3 |
| 7 | Tulsa | 6 | 1189 | 1289 | 436 | 2478 | 5.68 | 413.0 |
| 8 | Houston | 7 | 1089 | 1864 | 518 | 2953 | 5.70 | 421.9 |
| 9 | UCF | 7 | 1368 | 1646 | 465 | 3014 | 6.48 | 430.6 |
| 10 | Temple | 5 | 1032 | 1245 | 361 | 2277 | 6.31 | 455.4 |
| 11 | South Florida | 6 | 1372 | 1597 | 387 | 2969 | 7.67 | 494.8 |