2022 American Athletic Conference Leaders Interceptions - Games in October Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Julius Wood | ECU | JR | SAF | 5 | 1 | 47 | 1 | 0.20 |
| 2 | Layton Jordan | Temple | JR | OLB | 4 | 1 | 35 | 1 | 0.25 |
| 3 | Malik Fleming | ECU | JR | CB | 5 | 2 | 34 | 0 | 0.40 |
| 4 | Jayce Rogers | Houston | SR | DB | 3 | 1 | 28 | 0 | 0.33 |
| 4 | Art Green | Houston | SR | DB | 3 | 1 | 28 | 0 | 0.33 |
| 6 | Xavier Cullens | Memphis | SR | LB | 4 | 1 | 22 | 0 | 0.25 |
| 7 | Deshawn Pace | Cincinnati | JR | LB | 4 | 1 | 18 | 1 | 0.25 |
| 7 | Nicholas Straw | Navy | SR | RDR | 5 | 1 | 18 | 0 | 0.20 |
| 9 | Arquon Bush | Cincinnati | SR | CB | 4 | 1 | 15 | 0 | 0.25 |
| 9 | Cincir Evans | Memphis | SR | LB | 4 | 1 | 15 | 0 | 0.25 |
| 11 | Gerard Stringer | ECU | SR | SAF | 5 | 1 | 10 | 0 | 0.20 |
| 12 | Larry Brooks | Tulane | SR | S | 3 | 2 | 7 | 0 | 0.67 |
| 13 | Macon Clark | Tulane | SR | S | 3 | 1 | 6 | 0 | 0.33 |
| 14 | Justin Wright | Tulsa | SR | LB | 4 | 1 | 5 | 0 | 0.25 |
| 14 | Colin Ramos | Navy | SO | LB | 5 | 1 | 5 | 0 | 0.20 |
| 16 | Quindell Johnson | Memphis | SR | DB | 3 | 1 | 4 | 0 | 0.33 |
| 16 | Jalen McMurray | Temple | FR | CB | 4 | 1 | 4 | 0 | 0.25 |
| 18 | Elias Larry | Navy | SO | CB | 5 | 2 | 3 | 0 | 0.40 |
| 18 | Jireh Wilson | ECU | JR | SAF | 5 | 1 | 3 | 0 | 0.20 |