2022 American Athletic Conference Leaders Interceptions - Games in November Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Nick Roberts | SMU | SR | S | 4 | 2 | 61 | 0 | 0.50 |
| 2 | Xavier Cullens | Memphis | SR | LB | 4 | 1 | 54 | 1 | 0.25 |
| 3 | Muheem McCargo | Temple | SO | SAF | 4 | 1 | 35 | 0 | 0.25 |
| 4 | Mbiti Williams Jr. | Navy | SO | CB | 3 | 1 | 31 | 0 | 0.33 |
| 5 | Kendarin Ray | Tulsa | SR | S | 4 | 1 | 23 | 0 | 0.25 |
| 6 | Jahari Rogers | SMU | SO | CB | 4 | 2 | 20 | 0 | 0.50 |
| 7 | Malik Fleming | ECU | JR | CB | 3 | 1 | 15 | 0 | 0.33 |
| 7 | Quindell Johnson | Memphis | SR | DB | 4 | 1 | 15 | 0 | 0.25 |
| 9 | Divaad Wilson | UCF | SR | DB | 3 | 1 | 12 | 0 | 0.33 |
| 10 | Lummie Young IV | Tulane | SR | S | 4 | 1 | 6 | 0 | 0.25 |
| 11 | Juan Powell | ECU | SO | CB | 3 | 1 | 2 | 0 | 0.33 |