2022 Atlantic Coast Conference Leaders Total Defense - Games vs. FBS Teams With Non-Winning Record Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Clemson | 4 | 134 | 763 | 243 | 897 | 3.69 | 224.3 |
| 2 | Virginia | 3 | 292 | 506 | 212 | 798 | 3.76 | 266.0 |
| 3 | Syracuse | 3 | 335 | 495 | 187 | 830 | 4.44 | 276.7 |
| 4 | Boston College | 3 | 463 | 423 | 192 | 886 | 4.61 | 295.3 |
| 5 | North Carolina State | 3 | 170 | 612 | 166 | 782 | 4.71 | 260.7 |
| 6 | Pittsburgh | 6 | 696 | 1154 | 392 | 1850 | 4.72 | 308.3 |
| 7 | Wake Forest | 4 | 508 | 837 | 283 | 1345 | 4.75 | 336.3 |
| 8 | Florida State | 6 | 934 | 1000 | 404 | 1934 | 4.79 | 322.3 |
| 9 | Virginia Tech | 5 | 623 | 1123 | 355 | 1746 | 4.92 | 349.2 |
| 10 | Miami (Florida) | 4 | 450 | 761 | 244 | 1211 | 4.96 | 302.8 |
| 11 | Louisville | 3 | 198 | 727 | 179 | 925 | 5.17 | 308.3 |
| 12 | Georgia Tech | 3 | 511 | 557 | 202 | 1068 | 5.29 | 356.0 |
| 13 | Duke | 8 | 845 | 2093 | 544 | 2938 | 5.40 | 367.3 |
| 14 | North Carolina | 6 | 1036 | 1636 | 454 | 2672 | 5.89 | 445.3 |