2022 Atlantic Coast Conference Leaders Total Defense - Games vs. FBS Teams With Winning Record Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Duke | 4 | 510 | 1115 | 284 | 1625 | 5.72 | 406.3 |
| 2 | Virginia Tech | 5 | 826 | 1312 | 356 | 2138 | 6.01 | 427.6 |
| 3 | Pittsburgh | 6 | 515 | 1638 | 390 | 2153 | 5.52 | 358.8 |
| 4 | Florida State | 6 | 1006 | 1079 | 412 | 2085 | 5.06 | 347.5 |
| 5 | Virginia | 6 | 1070 | 1378 | 438 | 2448 | 5.59 | 408.0 |
| 6 | Miami (Florida) | 7 | 1162 | 1787 | 461 | 2949 | 6.40 | 421.3 |
| 7 | North Carolina | 7 | 1221 | 1883 | 475 | 3104 | 6.53 | 443.4 |
| 8 | Boston College | 8 | 1457 | 1822 | 542 | 3279 | 6.05 | 409.9 |
| 9 | Wake Forest | 8 | 1173 | 2513 | 579 | 3686 | 6.37 | 460.8 |
| 10 | Georgia Tech | 8 | 1640 | 1721 | 589 | 3361 | 5.71 | 420.1 |
| 11 | Clemson | 9 | 1179 | 2222 | 613 | 3401 | 5.55 | 377.9 |
| 12 | North Carolina State | 9 | 1103 | 2215 | 623 | 3318 | 5.33 | 368.7 |
| 13 | Syracuse | 9 | 1512 | 1889 | 647 | 3401 | 5.26 | 377.9 |
| 14 | Louisville | 10 | 1544 | 1834 | 669 | 3378 | 5.05 | 337.8 |