2022 Big 12 Conference Leaders Passes Defended - Games at Home Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 7 | 9 | 31 | 40 | 5.71 |
| 2 | TCU | 6 | 8 | 31 | 39 | 6.50 |
| 3 | Oklahoma | 6 | 9 | 27 | 36 | 6.00 |
| 4 | Baylor | 6 | 2 | 27 | 29 | 4.83 |
| 5 | Kansas State | 7 | 11 | 17 | 28 | 4.00 |
| 5 | Iowa State | 7 | 4 | 24 | 28 | 4.00 |
| 7 | Kansas | 6 | 6 | 20 | 26 | 4.33 |
| 7 | Texas | 7 | 4 | 22 | 26 | 3.71 |
| 9 | Texas Tech | 7 | 7 | 17 | 24 | 3.43 |
| 10 | West Virginia | 6 | 3 | 15 | 18 | 3.00 |