2022 Big 12 Conference Leaders Passes Defended - Games vs. FBS Teams With Winning Record Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | TCU | 8 | 9 | 41 | 50 | 6.25 |
| 2 | Oklahoma | 6 | 7 | 30 | 37 | 6.17 |
| 3 | Kansas | 8 | 6 | 29 | 35 | 4.38 |
| 4 | Texas | 7 | 4 | 30 | 34 | 4.86 |
| 5 | Oklahoma State | 5 | 5 | 24 | 29 | 5.80 |
| 5 | Texas Tech | 7 | 5 | 24 | 29 | 4.14 |
| 7 | Baylor | 7 | 7 | 21 | 28 | 4.00 |
| 8 | Kansas State | 7 | 7 | 20 | 27 | 3.86 |
| 9 | Iowa State | 7 | 5 | 15 | 20 | 2.86 |
| 10 | West Virginia | 6 | 2 | 16 | 18 | 3.00 |