2022 Big 12 Conference Leaders Passes Defended - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | TCU | 5 | 6 | 27 | 33 | 6.60 |
| 2 | Oklahoma | 4 | 4 | 16 | 20 | 5.00 |
| 2 | Oklahoma State | 4 | 2 | 18 | 20 | 5.00 |
| 4 | Texas Tech | 4 | 4 | 14 | 18 | 4.50 |
| 5 | Iowa State | 3 | 4 | 12 | 16 | 5.33 |
| 5 | Kansas State | 4 | 7 | 9 | 16 | 4.00 |
| 5 | Kansas | 4 | 3 | 13 | 16 | 4.00 |
| 5 | Baylor | 4 | 0 | 16 | 16 | 4.00 |
| 9 | Texas | 4 | 3 | 12 | 15 | 3.75 |
| 10 | West Virginia | 3 | 1 | 8 | 9 | 3.00 |