2021 Pac-12 Conference Leaders Long All Purpose Plays - Games in November Only through 01/10/2022
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| Name | Team | Yr | Pos | G | Yards | Yards | Yards | Yards | Yards | Yards | Yards | |
| 1 | Kazmeir Allen | UCLA | JR | RB | 3 | 4 | 3 | 2 | 1 | 1 | 1 | 1 |
| 1 | Giles Jackson | Washington | SO | WR | 4 | 4 | 3 | 0 | 0 | 0 | 0 | 0 |
| 1 | Calvin Jackson Jr. | Wash St | SR | WR | 3 | 3 | 3 | 2 | 2 | 2 | 0 | 0 |
| 4 | Daniel Arias | Colorado | JR | WR | 4 | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| 4 | Jarek Broussard | Colorado | SO | TB | 3 | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| 4 | Gary Bryant Jr. | USC | SO | WR | 3 | 6 | 2 | 1 | 1 | 0 | 0 | 0 |
| 4 | Kyle Philips | UCLA | JR | WR | 3 | 2 | 2 | 1 | 1 | 1 | 1 | 0 |
| 4 | TJ Pledger | Utah | JR | RB | 4 | 3 | 2 | 1 | 1 | 1 | 1 | 1 |
| 4 | Nikko Remigio | California | SR | WR | 2 | 2 | 2 | 2 | 1 | 0 | 0 | 0 |
| 4 | Dorian Singer | Arizona | FR | WR | 4 | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| 4 | Rachaad White | Ariz St | SR | RB | 4 | 3 | 2 | 1 | 0 | 0 | 0 | 0 |
| 12 | Drake Anderson | Arizona | SO | RB | 4 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 12 | Max Borghi | Wash St | SR | RB | 3 | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| 12 | Trevon Bradford | Oregon St | SR | WR | 4 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 12 | Christopher Brooks | California | SR | RB | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 12 | Carson Bruener | Washington | FR | LB | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 12 | Trevon Clark | California | SR | WR | 3 | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Jack Colletto | Oregon St | JR | ILB | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 12 | Britain Covey | Utah | JR | WR | 4 | 3 | 1 | 1 | 1 | 1 | 0 | 0 |
| 12 | Marcel Dancy | California | SR | RB | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| 12 | Jayden Daniels | Ariz St | JR | QB | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 12 | Greg Dulcich | UCLA | JR | TE | 3 | 4 | 1 | 1 | 0 | 0 | 0 | 0 |
| 12 | Travis Dye | Oregon | JR | RB | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 12 | Ethan Fernea | UCLA | SR | RB | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 12 | Kris Hutson | Oregon | FR | WR | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 12 | Jack Jones | Ariz St | SR | DB | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| 12 | Brant Kuithe | Utah | JR | TE | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 12 | Rome Odunze | Washington | FR | WR | 4 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 12 | Mark Perry | Colorado | SO | S | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 12 | Will Plummer | Arizona | FR | QB | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 12 | Ja'Lynn Polk | Washington | FR | WR | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 12 | Nikko Reed | Colorado | FR | CB | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 12 | Justus Rogers | Wash St | SR | LB | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| 12 | Tavion Thomas | Utah | SO | RB | 3 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| 12 | Jaylen Watson | Wash St | SR | DB | 3 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 12 | Devon Williams | Oregon | SO | WR | 4 | 3 | 1 | 1 | 0 | 0 | 0 | 0 |
| 12 | Mykael Wright | Oregon | SO | CB | 4 | 3 | 1 | 1 | 0 | 0 | 0 | 0 |
| 12 | Benjamin Yurosek | Stanford | SO | TE | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |