2021 Mid-American Conference Leaders Passing Defense - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Western Michigan | 12 | 302 | 169 | 56.0 | 2394 | 7.9 | 23 | 3 | 145.69 | 25.2 | 199.5 |
| 2 | Toledo | 12 | 389 | 219 | 56.3 | 2449 | 6.3 | 16 | 7 | 119.16 | 32.4 | 204.1 |
| 3 | Bowling Green | 11 | 280 | 167 | 59.6 | 2102 | 7.5 | 15 | 10 | 133.24 | 25.5 | 191.1 |
| 3 | Eastern Michigan | 12 | 364 | 217 | 59.6 | 2883 | 7.9 | 19 | 7 | 139.53 | 30.3 | 240.3 |
| 5 | Northern Illinois | 13 | 382 | 232 | 60.7 | 3167 | 8.3 | 27 | 3 | 152.12 | 29.4 | 243.6 |
| 6 | Miami (Ohio) | 12 | 362 | 220 | 60.8 | 2715 | 7.5 | 20 | 9 | 137.03 | 30.2 | 226.3 |
| 7 | Central Michigan | 12 | 414 | 252 | 60.9 | 3367 | 8.1 | 22 | 5 | 144.31 | 34.5 | 280.6 |
| 8 | Buffalo | 11 | 283 | 176 | 62.2 | 2572 | 9.1 | 20 | 3 | 159.73 | 25.7 | 233.8 |
| 9 | Kent State | 13 | 451 | 291 | 64.5 | 3578 | 7.9 | 23 | 12 | 142.67 | 34.7 | 275.2 |
| 10 | Ball State | 12 | 355 | 233 | 65.6 | 2743 | 7.7 | 15 | 14 | 136.59 | 29.6 | 228.6 |
| 11 | Akron | 11 | 276 | 184 | 66.7 | 2505 | 9.1 | 25 | 6 | 168.45 | 25.1 | 227.7 |
| 12 | Ohio | 11 | 353 | 238 | 67.4 | 2677 | 7.6 | 16 | 6 | 142.69 | 32.1 | 243.4 |