2021 Mid-American Conference Leaders Passing Defense - Games in October Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Western Michigan | 4 | 106 | 54 | 50.9 | 837 | 7.9 | 8 | 0 | 142.18 | 26.5 | 209.3 |
| 2 | Toledo | 4 | 113 | 61 | 54.0 | 701 | 6.2 | 3 | 3 | 109.54 | 28.3 | 175.3 |
| 3 | Eastern Michigan | 4 | 135 | 74 | 54.8 | 820 | 6.1 | 1 | 1 | 106.81 | 33.8 | 205.0 |
| 4 | Northern Illinois | 4 | 154 | 85 | 55.2 | 1113 | 7.2 | 8 | 1 | 131.75 | 38.5 | 278.3 |
| 5 | Buffalo | 5 | 118 | 69 | 58.5 | 1099 | 9.3 | 9 | 1 | 160.20 | 23.6 | 219.8 |
| 6 | Central Michigan | 4 | 117 | 71 | 60.7 | 1099 | 9.4 | 7 | 1 | 157.61 | 29.3 | 274.8 |
| 7 | Bowling Green | 5 | 128 | 81 | 63.3 | 1042 | 8.1 | 9 | 3 | 150.17 | 25.6 | 208.4 |
| 8 | Miami (Ohio) | 4 | 153 | 97 | 63.4 | 1102 | 7.2 | 8 | 2 | 138.56 | 38.3 | 275.5 |
| 9 | Kent State | 4 | 156 | 102 | 65.4 | 1129 | 7.2 | 5 | 4 | 131.63 | 39.0 | 282.3 |
| 10 | Ball State | 4 | 125 | 82 | 65.6 | 897 | 7.2 | 3 | 6 | 124.20 | 31.3 | 224.3 |
| 11 | Akron | 4 | 99 | 65 | 65.7 | 799 | 8.1 | 9 | 4 | 155.38 | 24.8 | 199.8 |
| 12 | Ohio | 4 | 116 | 82 | 70.7 | 986 | 8.5 | 6 | 3 | 153.99 | 29.0 | 246.5 |