2021 American Athletic Conference Leaders Fumbles Lost - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Fumbles | Fumbles Lost | Fumble Lost % | |
|---|---|---|---|---|---|
| 1 | University of Memphis | 1 | 0 | 0 | 0 |
| 1 | University of Houston | 1 | 1 | 0 | 0.00 |
| 3 | University of Central Florida | 1 | 1 | 1 | 100.00 |
| 3 | Southern Methodist University | 2 | 1 | 1 | 100.00 |
| 3 | University of Cincinnati | 3 | 2 | 1 | 50.00 |
| 3 | U.S. Naval Academy | 3 | 5 | 1 | 20.00 |
| 7 | Temple University | 2 | 3 | 2 | 66.67 |
| 7 | The University of Tulsa | 4 | 7 | 2 | 28.57 |
| 9 | University of South Florida | 4 | 7 | 3 | 42.86 |
| 10 | East Carolina University | 2 | 6 | 4 | 66.67 |
| 11 | Tulane University | 4 | 13 | 7 | 53.85 |