2021 American Athletic Conference Leaders Fumbles Lost - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Fumbles | Fumbles Lost | Fumble Lost % | |
|---|---|---|---|---|---|
| 1 | University of Houston | 9 | 6 | 2 | 33.33 |
| 2 | University of Memphis | 8 | 7 | 4 | 57.14 |
| 2 | Southern Methodist University | 8 | 8 | 4 | 50.00 |
| 2 | U.S. Naval Academy | 8 | 16 | 4 | 25.00 |
| 5 | University of Central Florida | 8 | 8 | 5 | 62.50 |
| 6 | University of Cincinnati | 9 | 10 | 6 | 60.00 |
| 6 | Tulane University | 8 | 13 | 6 | 46.15 |
| 8 | University of South Florida | 8 | 13 | 7 | 53.85 |
| 8 | The University of Tulsa | 8 | 14 | 7 | 50.00 |
| 10 | Temple University | 8 | 11 | 8 | 72.73 |
| 11 | East Carolina University | 8 | 14 | 9 | 64.29 |