2021 American Athletic Conference Leaders Tackles For Loss - Games vs. Conference Teams Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Cincinnati | 9 | 69.0 | 292 | 7.67 |
| 2 | UCF | 8 | 58.0 | 266 | 7.25 |
| 3 | Houston | 9 | 57.0 | 231 | 6.33 |
| 4 | Tulane | 8 | 56.0 | 212 | 7.00 |
| 5 | Memphis | 8 | 43.0 | 192 | 5.38 |
| 6 | SMU | 8 | 48.0 | 180 | 6.00 |
| 7 | Temple | 8 | 49.0 | 172 | 6.13 |
| 8 | East Carolina | 8 | 42.0 | 168 | 5.25 |
| 9 | Navy | 8 | 43.0 | 146 | 5.38 |
| 10 | South Florida | 8 | 38.0 | 120 | 4.75 |
| 11 | Tulsa | 8 | 40.0 | 119 | 5.00 |