2021 American Athletic Conference Leaders Sacks Allowed - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | SMU | 10 | 10.0 | 75 | 1.00 |
| 2 | Tulsa | 9 | 14.0 | 43 | 1.56 |
| 2 | Tulane | 8 | 14.0 | 79 | 1.75 |
| 4 | Cincinnati | 11 | 18.0 | 115 | 1.64 |
| 5 | South Florida | 8 | 21.0 | 165 | 2.63 |
| 6 | Temple | 10 | 22.0 | 126 | 2.20 |
| 7 | UCF | 12 | 24.0 | 156 | 2.00 |
| 8 | Navy | 9 | 25.0 | 130 | 2.78 |
| 9 | Memphis | 11 | 27.0 | 148 | 2.46 |
| 10 | East Carolina | 10 | 28.0 | 176 | 2.80 |
| 11 | Houston | 13 | 30.0 | 231 | 2.31 |