2021 American Athletic Conference Leaders Rushing Defense - From Opponent's 21 To 39 Yard Line through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 12 | 109 | 377 | 3.46 | 1 | 69 | 18 | 13 | 3 |
| 2 | Tulane | 12 | 120 | 513 | 4.28 | 1 | 68 | 23 | 15 | 5 |
| 3 | SMU | 12 | 162 | 570 | 3.52 | 0 | 34 | 27 | 18 | 7 |
| 4 | Temple | 12 | 133 | 588 | 4.42 | 1 | 75 | 29 | 13 | 2 |
| 5 | East Carolina | 12 | 136 | 500 | 3.68 | 0 | 40 | 31 | 20 | 4 |
| 5 | Tulsa | 13 | 152 | 649 | 4.27 | 0 | 64 | 31 | 20 | 3 |
| 5 | South Florida | 12 | 93 | 683 | 7.34 | 1 | 69 | 31 | 26 | 9 |
| 8 | UCF | 13 | 141 | 613 | 4.35 | 1 | 79 | 32 | 23 | 8 |
| 9 | Houston | 14 | 171 | 675 | 3.95 | 1 | 79 | 35 | 22 | 4 |
| 10 | Cincinnati | 14 | 195 | 695 | 3.56 | 0 | 51 | 39 | 19 | 2 |
| 11 | Memphis | 12 | 157 | 674 | 4.29 | 0 | 57 | 41 | 19 | 3 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||