2021 American Athletic Conference Leaders Rushing Defense - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Houston | 13 | 411 | 1462 | 3.56 | 13 | 31.62 | 112.46 |
| 2 | Navy | 12 | 390 | 1572 | 4.03 | 25 | 32.50 | 131.00 |
| 3 | SMU | 11 | 410 | 1532 | 3.74 | 15 | 37.27 | 139.27 |
| 4 | Tulsa | 12 | 433 | 1769 | 4.09 | 19 | 36.08 | 147.42 |
| 5 | Cincinnati | 13 | 546 | 1995 | 3.65 | 13 | 42.00 | 153.46 |
| 6 | East Carolina | 11 | 373 | 1809 | 4.85 | 18 | 33.91 | 164.45 |
| 7 | Tulane | 11 | 451 | 1857 | 4.12 | 25 | 41.00 | 168.82 |
| 8 | UCF | 12 | 465 | 2046 | 4.40 | 24 | 38.75 | 170.50 |
| 9 | Memphis | 11 | 461 | 1905 | 4.13 | 21 | 41.91 | 173.18 |
| 10 | South Florida | 11 | 400 | 2355 | 5.89 | 27 | 36.36 | 214.09 |
| 11 | Temple | 11 | 507 | 2523 | 4.98 | 32 | 46.09 | 229.36 |