2021 American Athletic Conference Leaders Rushing Defense - From Own 39 To 21 Yard Line through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Houston | 14 | 60 | 161 | 2.68 | 2 | 39 | 11 | 7 | 2 |
| 2 | SMU | 12 | 62 | 247 | 3.98 | 1 | 23 | 13 | 6 | 1 |
| 3 | Tulsa | 13 | 73 | 226 | 3.10 | 1 | 27 | 14 | 8 | 1 |
| 4 | Navy | 12 | 70 | 289 | 4.13 | 1 | 28 | 18 | 8 | 1 |
| 5 | Tulane | 12 | 103 | 400 | 3.88 | 3 | 35 | 22 | 14 | 5 |
| 6 | Cincinnati | 14 | 87 | 306 | 3.52 | 0 | 30 | 23 | 12 | 1 |
| 6 | UCF | 12 | 79 | 399 | 5.05 | 0 | 26 | 23 | 19 | 3 |
| 8 | Memphis | 12 | 80 | 350 | 4.38 | 3 | 36 | 24 | 13 | 5 |
| 9 | South Florida | 11 | 85 | 418 | 4.92 | 3 | 33 | 26 | 11 | 4 |
| 9 | East Carolina | 12 | 79 | 424 | 5.37 | 4 | 26 | 26 | 13 | 6 |
| 11 | Temple | 12 | 115 | 528 | 4.59 | 2 | 34 | 35 | 23 | 5 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||