2021 American Athletic Conference Leaders All Purpose - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Calvin Austin III | Memphis | SR | WR | 1 | 0 | 105 | 107 | 0 | 11 | 212 | 19.3 | 212.0 |
| 2 | Xavier Weaver | S Florida | JR | WR | 2 | 0 | 141 | 48 | 0 | 6 | 189 | 31.5 | 94.5 |
| 3 | Ryan Montgomery | Cincinnati | JR | RB | 2 | 3 | 0 | 42 | 0 | 4 | 45 | 11.3 | 22.5 |
| 4 | Jadan Blue | Temple | JR | WR | 2 | -1 | 49 | 20 | 0 | 9 | 68 | 7.6 | 34.0 |
| 5 | Amari Johnson | UCF | JR | WR | 2 | 4 | 23 | 18 | 0 | 5 | 45 | 9.0 | 22.5 |
| 6 | Marcus Jones | Houston | SR | CB | 1 | 4 | 0 | 13 | 0 | 7 | 17 | 2.4 | 17.0 |
| 7 | Keylon Stokes | Tulsa | SR | WR | 1 | 0 | 19 | 8 | 9 | 6 | 36 | 6.0 | 36.0 |
| 8 | Tyler Snead | ECU | SO | WR | 1 | 0 | 35 | 6 | 21 | 8 | 62 | 7.8 | 62.0 |
| 9 | Bryce Bohanon | Tulane | FR | WR | 1 | 0 | 0 | 4 | 0 | 1 | 4 | 4.0 | 4.0 |