2021 American Athletic Conference Leaders All Purpose - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jha'Quan Jackson | Tulane | SO | WR | 4 | 7 | 45 | 32 | 301 | 22 | 385 | 17.5 | 96.3 |
| 2 | Ryan Montgomery | Cincinnati | JR | RB | 3 | 4 | 23 | 29 | 0 | 8 | 56 | 7.0 | 18.7 |
| 3 | Chance Warren | Navy | SR | SB | 3 | 48 | 29 | 16 | 19 | 13 | 112 | 8.6 | 37.3 |
| 4 | Marcus Jones | Houston | SR | CB | 1 | 0 | 0 | 14 | 92 | 5 | 106 | 21.2 | 106.0 |
| 5 | Amad Anderson Jr. | Temple | SO | WR | 2 | 0 | 37 | 9 | 105 | 13 | 151 | 11.6 | 75.5 |
| 6 | Keylon Stokes | Tulsa | SR | WR | 2 | 0 | 52 | 8 | 9 | 11 | 69 | 6.3 | 34.5 |
| 6 | Kamdyn Benjamin | Tulsa | SO | WR | 4 | 0 | 0 | 8 | 0 | 3 | 8 | 2.7 | 2.0 |
| 8 | Bryce Bohanon | Tulane | FR | WR | 1 | 0 | 0 | 4 | 0 | 1 | 4 | 4.0 | 4.0 |