2021 American Athletic Conference Leaders All Purpose - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jha'Quan Jackson | Tulane | SO | WR | 2 | 0 | 0 | 0 | 240 | 10 | 240 | 24.0 | 120.0 |
| 2 | Tre Tucker | Cincinnati | JR | WR | 2 | 0 | 30 | -5 | 117 | 8 | 142 | 17.8 | 71.0 |
| 3 | Nathaniel Dell | Houston | SO | WR | 2 | 5 | 230 | 0 | 77 | 22 | 312 | 14.2 | 156.0 |
| 3 | Brian Battie | S Florida | SO | RB | 2 | 33 | 20 | 0 | 77 | 17 | 130 | 7.6 | 65.0 |
| 5 | Ryan O'Keefe | UCF | JR | WR | 2 | 110 | 159 | 0 | 75 | 18 | 344 | 19.1 | 172.0 |
| 6 | De'Von Fox | Temple | FR | WR | 2 | 0 | 0 | 0 | 61 | 3 | 61 | 20.3 | 30.5 |
| 7 | Johnny Richardson | UCF | SO | RB | 2 | 141 | 27 | 0 | 43 | 19 | 211 | 11.1 | 105.5 |
| 8 | Tyler Scott | Cincinnati | SO | WR | 2 | 0 | 60 | 0 | 40 | 7 | 100 | 14.3 | 50.0 |
| 9 | Ta'Zhawn Henry | Houston | JR | RB | 2 | -4 | 30 | 0 | 34 | 12 | 60 | 5.0 | 30.0 |
| 10 | Jimmy Horn Jr. | S Florida | FR | WR | 2 | -5 | 4 | 0 | 29 | 5 | 28 | 5.6 | 14.0 |
| 11 | Anthony Watkins | Tulsa | SO | RB | 2 | 53 | 8 | 0 | 23 | 11 | 84 | 7.6 | 42.0 |
| 12 | Tyler Snead | ECU | SO | WR | 1 | 0 | 35 | 6 | 21 | 8 | 62 | 7.8 | 62.0 |
| 13 | Ulysses Bentley IV | SMU | SO | RB | 1 | 153 | 13 | 0 | 20 | 23 | 186 | 8.1 | 186.0 |
| 14 | Jordan Ford | Tulsa | JR | RB | 1 | 3 | 0 | 0 | 14 | 2 | 17 | 8.5 | 17.0 |
| 15 | Rashee Rice | SMU | JR | WR | 1 | 0 | 20 | 0 | 10 | 5 | 30 | 6.0 | 30.0 |
| 15 | Kenney Solomon | Tulsa | SO | CB | 2 | 0 | 0 | 0 | 10 | 1 | 10 | 10.0 | 5.0 |
| 17 | Keylon Stokes | Tulsa | SR | WR | 1 | 0 | 19 | 8 | 9 | 6 | 36 | 6.0 | 36.0 |
| 18 | Sedrick Williams | Houston | JR | DL | 2 | 0 | 0 | 0 | 7 | 1 | 7 | 7.0 | 3.5 |