2021 American Athletic Conference Leaders Passing - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Tanner Mordecai | SMU | JR | QB | 10 | 391 | 269 | 68.8 | 3257 | 8.3 | 35 | 11 | 162.68 | 39.1 | 325.7 |
| 2 | Clayton Tune | Houston | JR | QB | 13 | 394 | 270 | 68.5 | 3296 | 8.4 | 28 | 9 | 157.68 | 30.3 | 253.5 |
| 3 | Desmond Ridder | Cincinnati | SR | QB | 11 | 306 | 204 | 66.7 | 2703 | 8.8 | 25 | 8 | 162.60 | 27.8 | 245.7 |
| 4 | Seth Henigan | Memphis | FR | QB | 10 | 348 | 214 | 61.5 | 3114 | 8.9 | 24 | 6 | 155.96 | 34.8 | 311.4 |
| 5 | Mikey Keene | UCF | FR | QB | 10 | 245 | 157 | 64.1 | 1589 | 6.5 | 16 | 4 | 136.84 | 24.5 | 158.9 |
| 6 | Holton Ahlers | ECU | JR | QB | 10 | 339 | 214 | 63.1 | 2624 | 7.7 | 15 | 9 | 137.44 | 33.9 | 262.4 |
| 7 | Davis Brin | Tulsa | JR | QB | 9 | 264 | 156 | 59.1 | 2174 | 8.2 | 14 | 11 | 137.43 | 29.3 | 241.6 |
| 7 | Michael Pratt | Tulane | FR | QB | 8 | 236 | 132 | 55.9 | 1705 | 7.2 | 14 | 8 | 129.42 | 29.5 | 213.1 |
| 9 | Dillon Gabriel | UCF | JR | QB | 3 | 102 | 70 | 68.6 | 814 | 8.0 | 9 | 3 | 158.90 | 34.0 | 271.3 |
| 10 | D'Wan Mathis | Temple | FR | QB | 6 | 169 | 100 | 59.2 | 1103 | 6.5 | 6 | 3 | 122.17 | 28.2 | 183.8 |
| 11 | Tai Lavatai | Navy | SO | QB | 8 | 45 | 23 | 51.1 | 333 | 7.4 | 5 | 1 | 145.50 | 5.6 | 41.6 |
| 12 | Justin Lynch | Temple | FR | QB | 9 | 124 | 74 | 59.7 | 681 | 5.5 | 4 | 2 | 113.23 | 13.8 | 75.7 |
| 13 | Justin Ibieta | Tulane | FR | QB | 1 | 21 | 13 | 61.9 | 166 | 7.9 | 2 | 2 | 140.69 | 21.0 | 166.0 |
| 13 | Timmy McClain | S Florida | FR | QB | 7 | 149 | 83 | 55.7 | 1042 | 7.0 | 2 | 1 | 117.54 | 21.3 | 148.9 |
| 13 | Ike Ogbogu | Houston | JR | QB | 6 | 35 | 20 | 57.1 | 256 | 7.3 | 2 | 1 | 131.73 | 5.8 | 42.7 |
| 13 | Tyler Snead | ECU | SO | WR | 10 | 4 | 2 | 50.0 | 102 | 25.5 | 2 | 0 | 429.20 | 0.4 | 10.2 |
| 13 | Ryan O'Keefe | UCF | JR | WR | 12 | 3 | 3 | 100.0 | 66 | 22.0 | 2 | 0 | 504.80 | 0.3 | 5.5 |
| 13 | Evan Prater | Cincinnati | FR | QB | 7 | 11 | 5 | 45.5 | 38 | 3.5 | 2 | 1 | 116.30 | 1.6 | 5.4 |
| 19 | Katravis Marsh | S Florida | SO | QB | 4 | 41 | 20 | 48.8 | 231 | 5.6 | 1 | 3 | 89.53 | 10.3 | 57.8 |
| 19 | Xavier Arline | Navy | SO | QB | 5 | 10 | 3 | 30.0 | 41 | 4.1 | 1 | 0 | 97.44 | 2.0 | 8.2 |
| 19 | Mason Garcia | ECU | FR | QB | 4 | 3 | 2 | 66.7 | 21 | 7.0 | 1 | 1 | 168.80 | 0.8 | 5.3 |
| 19 | Rodrigues Clark | Memphis | JR | RB | 9 | 1 | 1 | 100.0 | 40 | 40.0 | 1 | 0 | 766.00 | 0.1 | 4.4 |
| 19 | Joey Gatewood | UCF | JR | QB | 9 | 8 | 2 | 25.0 | 17 | 2.1 | 1 | 0 | 84.10 | 0.9 | 1.9 |
| 19 | Jordan Jones | Cincinnati | SR | WR | 4 | 1 | 1 | 100.0 | 5 | 5.0 | 1 | 0 | 472.00 | 0.3 | 1.3 |