2021 Atlantic Coast Conference Leaders Interceptions - Games Won Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 11 | 14 | 265 | 4 | 1.27 |
| 2 | Wake Forest | 11 | 14 | 177 | 1 | 1.27 |
| 3 | Louisville | 6 | 7 | 97 | 1 | 1.17 |
| 4 | Florida State | 5 | 7 | 72 | 1 | 1.40 |
| 5 | North Carolina | 6 | 9 | 71 | 0 | 1.50 |
| 5 | Miami (Florida) | 7 | 6 | 71 | 0 | 0.86 |
| 7 | Clemson | 10 | 11 | 66 | 1 | 1.10 |
| 8 | Duke | 3 | 5 | 55 | 0 | 1.67 |
| 9 | Virginia Tech | 6 | 6 | 39 | 0 | 1.00 |
| 10 | North Carolina State | 9 | 12 | 30 | 1 | 1.33 |
| 11 | Virginia | 6 | 4 | 27 | 0 | 0.67 |
| 12 | Syracuse | 5 | 1 | 23 | 0 | 0.20 |
| 13 | Boston College | 6 | 7 | 15 | 1 | 1.17 |
| 14 | Georgia Tech | 3 | 3 | 6 | 0 | 1.00 |