2021 Atlantic Coast Conference Leaders Total Offense - Games at Home Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Duke | 7 | 1217 | 1926 | 578 | 3143 | 5.44 | 449.0 |
| 2 | Pittsburgh | 7 | 1044 | 2752 | 543 | 3796 | 6.99 | 542.3 |
| 3 | Virginia | 7 | 995 | 2544 | 509 | 3539 | 6.95 | 505.6 |
| 3 | Miami (Florida) | 7 | 1041 | 2279 | 509 | 3320 | 6.52 | 474.3 |
| 5 | North Carolina | 7 | 1819 | 1821 | 496 | 3640 | 7.34 | 520.0 |
| 6 | Florida State | 7 | 1478 | 1418 | 494 | 2896 | 5.86 | 413.7 |
| 7 | Wake Forest | 6 | 1109 | 1724 | 477 | 2833 | 5.94 | 472.2 |
| 8 | North Carolina State | 7 | 1079 | 1875 | 471 | 2954 | 6.27 | 422.0 |
| 9 | Syracuse | 7 | 1418 | 1238 | 463 | 2656 | 5.74 | 379.4 |
| 10 | Clemson | 6 | 1281 | 1341 | 457 | 2622 | 5.74 | 437.0 |
| 11 | Louisville | 7 | 1443 | 1572 | 449 | 3015 | 6.71 | 430.7 |
| 12 | Virginia Tech | 7 | 1231 | 1314 | 445 | 2545 | 5.72 | 363.6 |
| 13 | Boston College | 6 | 1105 | 995 | 395 | 2100 | 5.32 | 350.0 |
| 14 | Georgia Tech | 6 | 996 | 1157 | 377 | 2153 | 5.71 | 358.8 |