2021 Atlantic Coast Conference Leaders Passing Defense - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 9 | 315 | 167 | 53.0 | 1879 | 6.0 | 15 | 9 | 113.13 | 35.0 | 208.8 |
| 2 | Clemson | 11 | 395 | 235 | 59.5 | 2467 | 6.2 | 11 | 9 | 116.59 | 35.9 | 224.3 |
| 3 | Boston College | 9 | 237 | 138 | 58.2 | 1623 | 6.8 | 11 | 6 | 126.01 | 26.3 | 180.3 |
| 4 | Florida State | 9 | 291 | 173 | 59.5 | 2061 | 7.1 | 19 | 11 | 132.93 | 32.3 | 229.0 |
| 5 | Syracuse | 9 | 264 | 170 | 64.4 | 1892 | 7.2 | 18 | 3 | 144.82 | 29.3 | 210.2 |
| 5 | Louisville | 10 | 358 | 227 | 63.4 | 2588 | 7.2 | 14 | 7 | 133.13 | 35.8 | 258.8 |
| 5 | Miami (Florida) | 10 | 365 | 230 | 63.0 | 2639 | 7.2 | 20 | 6 | 138.53 | 36.5 | 263.9 |
| 8 | Wake Forest | 11 | 343 | 202 | 58.9 | 2548 | 7.4 | 18 | 11 | 132.20 | 31.2 | 231.6 |
| 9 | Pittsburgh | 11 | 414 | 252 | 60.9 | 3116 | 7.5 | 22 | 15 | 134.39 | 37.6 | 283.3 |
| 10 | Virginia | 9 | 300 | 175 | 58.3 | 2270 | 7.6 | 20 | 7 | 139.22 | 33.3 | 252.2 |
| 11 | Virginia Tech | 10 | 303 | 176 | 58.1 | 2333 | 7.7 | 16 | 7 | 135.58 | 30.3 | 233.3 |
| 12 | North Carolina | 10 | 319 | 194 | 60.8 | 2681 | 8.4 | 25 | 9 | 151.63 | 31.9 | 268.1 |
| 13 | Duke | 10 | 354 | 210 | 59.3 | 3361 | 9.5 | 29 | 8 | 161.58 | 35.4 | 336.1 |
| 14 | Georgia Tech | 9 | 272 | 182 | 66.9 | 2727 | 10.0 | 23 | 1 | 178.29 | 30.2 | 303.0 |