2021 Atlantic Coast Conference Leaders Passing Defense - On 2nd Down through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 12 | 134 | 67 | 50.0 | 683 | 8 | 5 | 105.05 | 34 | 31 | 15 | 5 |
| 2 | Clemson | 13 | 151 | 81 | 53.6 | 760 | 2 | 4 | 94.99 | 39 | 37 | 15 | 5 |
| 3 | Florida State | 12 | 126 | 71 | 56.3 | 767 | 5 | 6 | 111.05 | 44 | 36 | 17 | 7 |
| 4 | Miami (Florida) | 12 | 136 | 80 | 58.8 | 817 | 4 | 3 | 114.58 | 46 | 34 | 16 | 9 |
| 5 | Boston College | 12 | 106 | 65 | 61.3 | 822 | 6 | 3 | 139.48 | 79 | 38 | 20 | 6 |
| 6 | Syracuse | 12 | 120 | 82 | 68.3 | 830 | 10 | 0 | 153.93 | 58 | 40 | 19 | 8 |
| 7 | Louisville | 13 | 136 | 85 | 62.5 | 847 | 4 | 5 | 117.18 | 51 | 44 | 18 | 6 |
| 8 | North Carolina | 13 | 114 | 75 | 65.8 | 848 | 7 | 2 | 145.03 | 69 | 35 | 15 | 9 |
| 9 | Virginia Tech | 13 | 137 | 84 | 61.3 | 903 | 8 | 4 | 130.10 | 55 | 44 | 21 | 8 |
| 10 | Virginia | 12 | 116 | 74 | 63.8 | 906 | 4 | 3 | 135.60 | 59 | 45 | 21 | 8 |
| 11 | Georgia Tech | 12 | 103 | 67 | 65.0 | 916 | 7 | 1 | 160.24 | 77 | 45 | 22 | 9 |
| 12 | Pittsburgh | 14 | 158 | 78 | 49.4 | 925 | 6 | 5 | 104.74 | 76 | 44 | 20 | 5 |
| 13 | Wake Forest | 14 | 126 | 76 | 60.3 | 967 | 6 | 4 | 134.15 | 75 | 47 | 19 | 9 |
| 14 | Duke | 12 | 123 | 80 | 65.0 | 1098 | 10 | 2 | 163.61 | 47 | 48 | 30 | 13 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||