2021 Atlantic Coast Conference Leaders Passing Defense - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 8 | 266 | 134 | 50.4 | 1585 | 6.0 | 13 | 9 | 109.80 | 33.3 | 198.1 |
| 2 | Louisville | 8 | 307 | 190 | 61.9 | 2058 | 6.7 | 13 | 7 | 127.62 | 38.4 | 257.3 |
| 3 | Boston College | 8 | 195 | 108 | 55.4 | 1320 | 6.8 | 10 | 4 | 125.07 | 24.4 | 165.0 |
| 4 | Clemson | 8 | 284 | 171 | 60.2 | 1965 | 6.9 | 10 | 5 | 126.43 | 35.5 | 245.6 |
| 4 | Miami (Florida) | 8 | 295 | 184 | 62.4 | 2024 | 6.9 | 12 | 6 | 129.35 | 36.9 | 253.0 |
| 6 | Florida State | 8 | 260 | 152 | 58.5 | 1843 | 7.1 | 17 | 8 | 133.43 | 32.5 | 230.4 |
| 7 | Syracuse | 8 | 236 | 148 | 62.7 | 1747 | 7.4 | 17 | 3 | 146.13 | 29.5 | 218.4 |
| 7 | Virginia Tech | 8 | 251 | 140 | 55.8 | 1865 | 7.4 | 12 | 6 | 129.19 | 31.4 | 233.1 |
| 9 | Pittsburgh | 9 | 331 | 201 | 60.7 | 2524 | 7.6 | 17 | 13 | 133.88 | 36.8 | 280.4 |
| 10 | Wake Forest | 10 | 310 | 184 | 59.4 | 2383 | 7.7 | 18 | 9 | 137.28 | 31.0 | 238.3 |
| 11 | Virginia | 8 | 255 | 151 | 59.2 | 2049 | 8.0 | 19 | 6 | 146.59 | 31.9 | 256.1 |
| 11 | North Carolina | 9 | 304 | 182 | 59.9 | 2439 | 8.0 | 23 | 9 | 146.31 | 33.8 | 271.0 |
| 13 | Georgia Tech | 8 | 252 | 168 | 66.7 | 2472 | 9.8 | 19 | 1 | 173.16 | 31.5 | 309.0 |
| 13 | Duke | 8 | 283 | 172 | 60.8 | 2778 | 9.8 | 25 | 3 | 170.26 | 35.4 | 347.3 |