2021 Atlantic Coast Conference Leaders Rushing Defense - When The Game Is Tied through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Miami (Florida) | 11 | 58 | 202 | 3.48 | 4 | 51 | 12 | 6 | 3 |
| 1 | Florida State | 11 | 71 | 225 | 3.17 | 1 | 14 | 12 | 6 | 0 |
| 3 | Pittsburgh | 13 | 90 | 232 | 2.58 | 4 | 23 | 15 | 7 | 1 |
| 3 | Duke | 12 | 62 | 250 | 4.03 | 2 | 25 | 12 | 7 | 3 |
| 3 | North Carolina | 9 | 53 | 296 | 5.58 | 2 | 37 | 15 | 7 | 4 |
| 3 | Virginia Tech | 10 | 59 | 307 | 5.20 | 4 | 80 | 15 | 7 | 1 |
| 3 | Georgia Tech | 11 | 76 | 318 | 4.18 | 5 | 35 | 17 | 7 | 2 |
| 3 | Clemson | 10 | 101 | 393 | 3.89 | 3 | 54 | 19 | 7 | 5 |
| 9 | North Carolina State | 11 | 80 | 245 | 3.06 | 0 | 33 | 13 | 9 | 3 |
| 9 | Louisville | 11 | 106 | 341 | 3.22 | 5 | 29 | 19 | 9 | 1 |
| 11 | Virginia | 9 | 50 | 261 | 5.22 | 1 | 20 | 14 | 11 | 1 |
| 11 | Wake Forest | 10 | 58 | 303 | 5.22 | 2 | 58 | 15 | 11 | 2 |
| 13 | Boston College | 10 | 106 | 504 | 4.75 | 4 | 59 | 27 | 13 | 4 |
| 14 | Syracuse | 11 | 129 | 529 | 4.10 | 5 | 39 | 35 | 17 | 5 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||