2021 Big 12 Conference Leaders First Downs - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 13 | 136 | 145 | 34 | 315 | 24.2 |
| 2 | Iowa State | 12 | 87 | 155 | 21 | 263 | 21.9 |
| 2 | West Virginia | 12 | 94 | 134 | 21 | 249 | 20.8 |
| 4 | Oklahoma | 12 | 99 | 142 | 19 | 260 | 21.7 |
| 5 | Texas Tech | 12 | 99 | 126 | 18 | 243 | 20.3 |
| 6 | TCU | 11 | 106 | 105 | 15 | 226 | 20.5 |
| 7 | Kansas State | 12 | 94 | 102 | 14 | 210 | 17.5 |
| 8 | Texas | 12 | 120 | 114 | 13 | 247 | 20.6 |
| 9 | Baylor | 13 | 135 | 109 | 12 | 256 | 19.7 |
| 10 | Kansas | 11 | 81 | 92 | 10 | 183 | 16.6 |