2021 Big 12 Conference Leaders Tackles For Loss - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Oklahoma State | 10 | 83.0 | 353 | 8.30 |
| 2 | Oklahoma | 10 | 72.0 | 300 | 7.20 |
| 3 | West Virginia | 10 | 71.0 | 283 | 7.10 |
| 4 | Kansas State | 10 | 70.0 | 241 | 7.00 |
| 5 | Baylor | 9 | 62.0 | 230 | 6.89 |
| 6 | Iowa State | 8 | 50.0 | 205 | 6.25 |
| 7 | Texas Tech | 9 | 44.0 | 166 | 4.89 |
| 8 | Texas | 7 | 39.0 | 123 | 5.57 |
| 9 | TCU | 9 | 32.0 | 130 | 3.56 |
| 9 | Kansas | 9 | 32.0 | 129 | 3.56 |