2021 Big 12 Conference Leaders Tackles For Loss - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Baylor | 4 | 35.0 | 174 | 8.75 |
| 2 | West Virginia | 4 | 34.0 | 140 | 8.50 |
| 3 | Oklahoma | 4 | 33.0 | 130 | 8.25 |
| 4 | Texas Tech | 4 | 30.0 | 126 | 7.50 |
| 5 | Iowa State | 4 | 27.0 | 102 | 6.75 |
| 6 | Oklahoma State | 4 | 26.0 | 117 | 6.50 |
| 7 | Kansas State | 4 | 24.0 | 104 | 6.00 |
| 8 | Texas | 3 | 18.0 | 51 | 6.00 |
| 9 | TCU | 3 | 12.0 | 37 | 4.00 |
| 10 | Kansas | 3 | 8.0 | 24 | 2.67 |