2021 Big 12 Conference Leaders Interceptions - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 4 | 6 | 147 | 1 | 1.50 |
| 2 | Kansas | 4 | 5 | 124 | 2 | 1.25 |
| 3 | West Virginia | 4 | 5 | 103 | 0 | 1.25 |
| 4 | Texas Tech | 5 | 3 | 81 | 1 | 0.60 |
| 5 | Baylor | 5 | 5 | 80 | 1 | 1.00 |
| 6 | Kansas State | 6 | 7 | 72 | 0 | 1.17 |
| 7 | Iowa State | 5 | 5 | 29 | 1 | 1.00 |
| 8 | TCU | 4 | 2 | 2 | 0 | 0.50 |
| 9 | Oklahoma | 6 | 2 | 0 | 0 | 0.33 |