2021 Big 12 Conference Leaders Passing - When Winning By 15+ Pts through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brock Purdy | Iowa State | SR | QB | 4 | 43 | 34 | 79.1 | 485 | 4 | 0 | 204.51 | 35 | 23 | 19 | 5 |
| 2 | Casey Thompson | Texas | JR | QB | 4 | 39 | 32 | 82.1 | 435 | 7 | 1 | 229.84 | 62 | 18 | 10 | 4 |
| 3 | Spencer Rattler | Oklahoma | SO | QB | 3 | 33 | 27 | 81.8 | 280 | 4 | 1 | 187.03 | 42 | 16 | 6 | 2 |
| 4 | Gerry Bohanon | Baylor | JR | QB | 4 | 39 | 25 | 64.1 | 293 | 3 | 0 | 152.59 | 41 | 14 | 7 | 3 |
| 5 | Caleb Williams | Oklahoma | FR | QB | 3 | 33 | 24 | 72.7 | 331 | 3 | 0 | 186.98 | 57 | 16 | 7 | 4 |
| 6 | Spencer Sanders | Okla St | JR | QB | 4 | 37 | 20 | 54.1 | 302 | 2 | 0 | 140.45 | 46 | 14 | 10 | 2 |
| 7 | Skylar Thompson | Kansas St | SR | QB | 3 | 30 | 19 | 63.3 | 268 | 2 | 0 | 160.37 | 73 | 11 | 5 | 3 |
| 8 | Jarret Doege | WVU | SR | QB | 2 | 19 | 13 | 68.4 | 197 | 3 | 0 | 207.61 | 39 | 8 | 7 | 3 |
| 8 | Shane Illingworth | Okla St | SO | QB | 2 | 25 | 13 | 52.0 | 189 | 2 | 1 | 133.90 | 40 | 7 | 5 | 3 |
| 10 | Tyler Shough | Texas Tech | JR | QB | 1 | 18 | 11 | 61.1 | 153 | 1 | 0 | 150.84 | 25 | 8 | 5 | 2 |
| 11 | Donovan Smith | Texas Tech | FR | QB | 3 | 13 | 9 | 69.2 | 164 | 0 | 0 | 175.20 | 48 | 3 | 4 | 2 |
| 11 | Max Duggan | TCU | JR | QB | 2 | 13 | 9 | 69.2 | 124 | 1 | 1 | 159.35 | 47 | 4 | 3 | 2 |
| 13 | Henry Colombi | Texas Tech | SR | QB | 2 | 10 | 8 | 80.0 | 66 | 1 | 0 | 168.44 | 25 | 5 | 1 | 1 |
| 13 | Blake Shapen | Baylor | FR | QB | 3 | 13 | 8 | 61.5 | 59 | 0 | 0 | 99.66 | 17 | 3 | 2 | 0 |
| 15 | Garrett Greene | WVU | FR | QB | 1 | 7 | 4 | 57.1 | 57 | 0 | 0 | 125.54 | 28 | 3 | 2 | 1 |
| 15 | Hunter Dekkers | Iowa State | FR | QB | 2 | 11 | 4 | 36.4 | 50 | 0 | 0 | 74.54 | 22 | 2 | 2 | 0 |
| 17 | Matthew Downing | TCU | JR | QB | 1 | 4 | 3 | 75.0 | 26 | 0 | 0 | 129.60 | 12 | 2 | 0 | 0 |
| 18 | Hudson Card | Texas | FR | QB | 1 | 3 | 2 | 66.7 | 29 | 0 | 0 | 147.87 | 22 | 1 | 1 | 0 |
| 18 | Will Crowder | WVU | FR | QB | 1 | 2 | 2 | 100.0 | 28 | 0 | 0 | 217.60 | 20 | 1 | 1 | 0 |
| 18 | Ralph Rucker | Oklahoma | FR | QB | 1 | 2 | 2 | 100.0 | 20 | 0 | 0 | 184.00 | 12 | 1 | 0 | 0 |
| 18 | Ethan Bullock | Okla St | SR | QB | 1 | 3 | 2 | 66.7 | 16 | 0 | 0 | 111.47 | 13 | 1 | 0 | 0 |
| 18 | Will Howard | Kansas St | SO | QB | 1 | 3 | 2 | 66.7 | 13 | 0 | 0 | 103.07 | 11 | 1 | 0 | 0 |
| 23 | Jacob Zeno | Baylor | SO | QB | 2 | 3 | 1 | 33.3 | 41 | 0 | 0 | 148.13 | 41 | 1 | 1 | 1 |
| 23 | Chandler Morris | TCU | FR | QB | 1 | 1 | 1 | 100.0 | 20 | 1 | 0 | 598.00 | 20 | 1 | 1 | 0 |
| 25 | Jalon Daniels | Kansas | SO | QB | 1 | 1 | 0 | 0.0 | 0 | 0 | 0 | 0.00 | 0 | 0 | 0 | 0 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | ||||||||||||||||