2019 Conference USA Leaders Total Defense - Games in October Only through 01/13/2020
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Florida International | 4 | 858 | 366 | 235 | 1224 | 5.21 | 306.0 |
| 2 | UAB | 3 | 299 | 376 | 188 | 675 | 3.59 | 225.0 |
| 3 | UTEP | 3 | 657 | 534 | 181 | 1191 | 6.58 | 397.0 |
| 4 | Western Kentucky | 4 | 449 | 609 | 233 | 1058 | 4.54 | 264.5 |
| 5 | Florida Atlantic | 3 | 448 | 675 | 208 | 1123 | 5.40 | 374.3 |
| 6 | UTSA | 3 | 443 | 698 | 192 | 1141 | 5.94 | 380.3 |
| 7 | Rice | 3 | 433 | 704 | 193 | 1137 | 5.89 | 379.0 |
| 8 | Southern Mississippi | 3 | 281 | 712 | 185 | 993 | 5.37 | 331.0 |
| 9 | Louisiana Tech | 3 | 340 | 775 | 218 | 1115 | 5.11 | 371.7 |
| 10 | Charlotte | 3 | 555 | 845 | 205 | 1400 | 6.83 | 466.7 |
| 11 | Old Dominion | 4 | 697 | 932 | 283 | 1629 | 5.76 | 407.3 |
| 12 | North Texas | 3 | 573 | 1012 | 225 | 1585 | 7.04 | 528.3 |
| 13 | Marshall | 4 | 417 | 1038 | 262 | 1455 | 5.55 | 363.8 |
| 14 | Middle Tennessee | 4 | 626 | 1146 | 298 | 1772 | 5.95 | 443.0 |