2020 Conference USA Leaders Total Defense - Games in October Only through 01/11/2021
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | UTEP | 2 | 235 | 304 | 128 | 539 | 4.21 | 269.5 |
| 2 | Florida International | 2 | 421 | 427 | 161 | 848 | 5.27 | 424.0 |
| 3 | Rice | 2 | 218 | 502 | 123 | 720 | 5.85 | 360.0 |
| 4 | Marshall | 3 | 178 | 617 | 189 | 795 | 4.21 | 265.0 |
| 5 | Florida Atlantic | 3 | 320 | 691 | 206 | 1011 | 4.91 | 337.0 |
| 6 | North Texas | 3 | 761 | 707 | 223 | 1468 | 6.58 | 489.3 |
| 7 | UAB | 4 | 461 | 736 | 265 | 1197 | 4.52 | 299.3 |
| 8 | Middle Tennessee | 4 | 1053 | 794 | 296 | 1847 | 6.24 | 461.8 |
| 9 | Charlotte | 4 | 758 | 811 | 249 | 1569 | 6.30 | 392.3 |
| 10 | UTSA | 5 | 971 | 845 | 334 | 1816 | 5.44 | 363.2 |
| 11 | Western Kentucky | 5 | 801 | 854 | 329 | 1655 | 5.03 | 331.0 |
| 12 | Southern Mississippi | 3 | 515 | 917 | 221 | 1432 | 6.48 | 477.3 |
| 13 | Louisiana Tech | 5 | 949 | 1102 | 362 | 2051 | 5.67 | 410.2 |