2018 Conference USA Leaders Passing Defense - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | North Texas | 1 | 45 | 20 | 44.4 | 210 | 4.7 | 0 | 6 | 56.97 | 45.0 | 210.0 |
| 2 | Florida International | 2 | 66 | 48 | 72.7 | 492 | 7.5 | 7 | 2 | 164.29 | 33.0 | 246.0 |
| 3 | Western Kentucky | 2 | 52 | 27 | 51.9 | 345 | 6.6 | 2 | 1 | 116.49 | 26.0 | 172.5 |
| 3 | Old Dominion | 1 | 34 | 17 | 50.0 | 282 | 8.3 | 3 | 1 | 142.91 | 34.0 | 282.0 |
| 3 | Rice | 2 | 54 | 41 | 75.9 | 615 | 11.4 | 6 | 1 | 204.57 | 27.0 | 307.5 |
| 6 | UTEP | 1 | 19 | 13 | 68.4 | 167 | 8.8 | 1 | 0 | 159.62 | 19.0 | 167.0 |
| 6 | Middle Tennessee | 3 | 52 | 37 | 71.2 | 514 | 9.9 | 7 | 0 | 198.60 | 17.3 | 171.3 |
| 6 | Charlotte | 1 | 21 | 16 | 76.2 | 172 | 8.2 | 1 | 0 | 160.70 | 21.0 | 172.0 |
| 6 | UAB | 1 | 20 | 11 | 55.0 | 192 | 9.6 | 2 | 0 | 168.64 | 20.0 | 192.0 |
| 6 | Louisiana Tech | 2 | 57 | 33 | 57.9 | 434 | 7.6 | 4 | 0 | 145.02 | 28.5 | 217.0 |
| 6 | Southern Mississippi | 1 | 33 | 19 | 57.6 | 245 | 7.4 | 2 | 0 | 139.94 | 33.0 | 245.0 |
| 6 | UTSA | 3 | 84 | 57 | 67.9 | 925 | 11.0 | 10 | 0 | 199.65 | 28.0 | 308.3 |
| 6 | Florida Atlantic | 1 | 23 | 19 | 82.6 | 334 | 14.5 | 3 | 0 | 247.63 | 23.0 | 334.0 |
| 6 | Marshall | 2 | 66 | 41 | 62.1 | 689 | 10.4 | 5 | 0 | 174.81 | 33.0 | 344.5 |