2016 Conference USA Leaders Passing Defense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Florida Atlantic | 2 | 49 | 30 | 61.2 | 350 | 7.1 | 1 | 2 | 119.80 | 24.5 | 175.0 |
| 1 | Southern Mississippi | 2 | 43 | 27 | 62.8 | 589 | 13.7 | 7 | 2 | 222.27 | 21.5 | 294.5 |
| 1 | Louisiana Tech | 2 | 65 | 46 | 70.8 | 661 | 10.2 | 7 | 2 | 185.58 | 32.5 | 330.5 |
| 4 | North Texas | 1 | 29 | 16 | 55.2 | 216 | 7.4 | 0 | 1 | 110.83 | 29.0 | 216.0 |
| 4 | Rice | 2 | 60 | 35 | 58.3 | 503 | 8.4 | 5 | 1 | 152.92 | 30.0 | 251.5 |
| 4 | UTSA | 2 | 63 | 34 | 54.0 | 512 | 8.1 | 3 | 1 | 134.78 | 31.5 | 256.0 |
| 4 | Western Kentucky | 2 | 71 | 43 | 60.6 | 630 | 8.9 | 3 | 1 | 146.21 | 35.5 | 315.0 |
| 4 | Marshall | 2 | 68 | 41 | 60.3 | 697 | 10.3 | 7 | 1 | 177.42 | 34.0 | 348.5 |
| 4 | Charlotte | 1 | 35 | 26 | 74.3 | 391 | 11.2 | 8 | 1 | 237.85 | 35.0 | 391.0 |
| 10 | Middle Tennessee | 2 | 68 | 35 | 51.5 | 394 | 5.8 | 3 | 0 | 114.70 | 34.0 | 197.0 |
| 10 | Florida International | 2 | 49 | 33 | 67.3 | 478 | 9.8 | 4 | 0 | 176.23 | 24.5 | 239.0 |
| 10 | UTEP | 1 | 28 | 23 | 82.1 | 245 | 8.8 | 4 | 0 | 202.78 | 28.0 | 245.0 |
| 10 | Old Dominion | 1 | 32 | 27 | 84.4 | 312 | 9.8 | 4 | 0 | 207.53 | 32.0 | 312.0 |