2018 Conference USA Leaders Total Defense - Games in October Only through 01/07/2019
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Charlotte | 3 | 204 | 622 | 181 | 826 | 4.56 | 275.3 |
| 2 | Southern Mississippi | 3 | 368 | 487 | 180 | 855 | 4.75 | 285.0 |
| 3 | Florida International | 3 | 474 | 401 | 195 | 875 | 4.49 | 291.7 |
| 4 | UAB | 4 | 282 | 682 | 240 | 964 | 4.02 | 241.0 |
| 5 | UTSA | 3 | 340 | 753 | 221 | 1093 | 4.95 | 364.3 |
| 6 | UTEP | 3 | 568 | 542 | 199 | 1110 | 5.58 | 370.0 |
| 7 | Florida Atlantic | 3 | 464 | 709 | 234 | 1173 | 5.01 | 391.0 |
| 8 | Marshall | 3 | 328 | 853 | 239 | 1181 | 4.94 | 393.7 |
| 9 | Western Kentucky | 3 | 589 | 735 | 217 | 1324 | 6.10 | 441.3 |
| 10 | Louisiana Tech | 4 | 613 | 742 | 268 | 1355 | 5.06 | 338.8 |
| 11 | North Texas | 4 | 452 | 1023 | 277 | 1475 | 5.32 | 368.8 |
| 12 | Rice | 4 | 724 | 879 | 250 | 1603 | 6.41 | 400.8 |
| 13 | Middle Tennessee | 4 | 610 | 1026 | 301 | 1636 | 5.44 | 409.0 |
| 14 | Old Dominion | 4 | 1000 | 1058 | 294 | 2058 | 7.00 | 514.5 |