2017 American Athletic Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 01/08/2018
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 1 | 30 | 145 | 54 | 175 | 3.24 | 175.0 |
| 2 | UCF | 2 | 132 | 486 | 152 | 618 | 4.07 | 309.0 |
| 3 | Cincinnati | 1 | 193 | 221 | 66 | 414 | 6.27 | 414.0 |
| 4 | Houston | 2 | 352 | 540 | 154 | 892 | 5.79 | 446.0 |
| 5 | South Florida | 2 | 200 | 703 | 149 | 903 | 6.06 | 451.5 |
| 6 | Memphis | 2 | 202 | 777 | 171 | 979 | 5.73 | 489.5 |
| 7 | Connecticut | 3 | 676 | 918 | 212 | 1594 | 7.52 | 531.3 |
| 8 | SMU | 1 | 254 | 365 | 79 | 619 | 7.84 | 619.0 |
| 9 | Tulane | 1 | 197 | 434 | 62 | 631 | 10.18 | 631.0 |
| 10 | Tulsa | 1 | 332 | 308 | 63 | 640 | 10.16 | 640.0 |
| 11 | East Carolina | 2 | 498 | 791 | 176 | 1289 | 7.32 | 644.5 |